Recreational Music-Making modulates natural killer cell activity, cytokines, and mood states in corporate employees.

Cytokines (Greek cyto-, cell; and -kinos, movement) are any of a number of substances that are secreted by specific cells of the immune system which carry signals locally between cells, and thus have an effect on other cells.)

Masatada  Wachi, Masahiro Koyama, Masanori  Utsuyama, Barry  Bittman, Masanobu  Kitagawa, Katsuiku  Hirokawa

Med Sci Monit 2007; 13(2):CR57-70


Background: With growing evidence linking job stress to illness, finding an effective means of stress management has become a challenging international endeavor. Although music therapy has attracted the attention of various fields as a promising method for alleviating stress, lack of standardization and paucity of data have served as impediments to widespread utilization.

Material/Methods: The effects of a Recreational Music-Making (RMM) group drumming protocol was evaluated on Japanese male corporate employees. A total of 20 volunteers participated in a one-hour RMM session while 20 volunteers engaged in leisurely reading for one hour (controls). After a six-month interval, the groups switched activities and underwent one session each. Pre- and post-intervention data were collected using mood state questionnaires and blood samples. Individual and group mean values for natural killer (NK) cell activity, NK cell percentage, and cytokine gene expression were analyzed.

Results: NK cell activity in the RMM group increased among individuals with low pre-intervention levels, and decreased among those with high pre-intervention levels. A significant correlation was established between changes in NK cell activity and the changes in the level of gene expressions for interferon-gamma and interleukin-10. The RMM group demonstrated enhanced mood, lower gene expression levels of the stress-induced cytokine interleukin-10, and higher NK cell activity when compared to the control.

Conclusions: Based upon documented changes in NK cell activity, coupled with gene expression changes for interferon-gamma, interleukin-10, and improved mood, this RMM protocol has significant potential for utilization in the corporate wellness environment.

Link to Medical Science Monitor Article

Drumatic Innovation Opportunities

Drum Classes are now available in Sandpoint, Idaho

Drum Repair is now available in Sandpoint, Idaho

Drum Tuning is now available in Sandpoint, Idaho

Drumming Reduces Stress

Drumming is Fantastic for Seniors

DailyBee Drum Circle

We invite you to contact us

*Call or E-Mail us Today*
Michael 208 627 9045
Molly 208 627 9045


Print Friendly